叶酸和维生素B-12的状态和睡眠时间在中年儿童
Mia Q Zhu1, Mercedes Mora-Plazas2, Eduardo Villamor1
1Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI, 48109, USA.
Sleep medicine
|June 5, 2025
概括
叶酸摄入量与儿童睡眠时间的延长有关,特别是当维生素B-12水平较低时. 这突显了这些营养素对中儿童期健康睡眠模式的重要性.
科学领域:
- 营养科学 营养科学
- 儿科健康 儿科健康
- 睡眠医学 睡眠医学
背景情况:
- 睡眠时间不足在儿童中期很常见,对健康构成重大风险.
- 叶酸和维生素B-12在儿童睡眠时间中的作用尚未得到充分研究,特别是它们的相互作用.
- 了解营养对睡眠的影响对于儿童的发展和福祉至关重要.
研究的目的:
- 研究红细胞叶酸和血维生素B-12与中儿童夜间睡眠时间的纵向关联.
- 为了检查叶酸和维生素B-12之间对睡眠时间的潜在相互作用.
- 为改善儿童睡眠的营养策略提供基于证据的见解.
主要方法:
- 波哥大学校儿童队伍中1642名儿童的纵向研究.
- 通过父母报告评估夜间睡眠时间,经过平均2年的随访后.
- 使用有限立方线的线性回归来估计关联和相互作用的统计分析.
主要成果:
- 红细胞叶酸度与夜间睡眠时间的非线性正相关.
- 与中位数相比,叶酸在第95百分位的儿童的睡眠时间明显更长.
- 观察到一种显著的相互作用:叶酸与睡眠的相关性仅在维生素B-12水平较低的儿童中明显.
结论:
- 红细胞叶酸与儿童的夜间睡眠时间有关,特别是那些维生素B-12水平较低的儿童.
- 研究结果表明,足够的叶酸状况,特别是与足够的维生素B-12相结合,可能对促进儿童足够睡眠很重要.
- 对营养与睡眠相互作用的进一步研究可以为儿童睡眠健康提供有针对性的营养干预措施.
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