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可生物降解的粉基纳米复合材料薄膜与激光合成的银纳米颗粒:包装的材料方法

Florencia Ortega¹, Jessica Minnaard¹, Valeria B Arce²

¹Centro de Investigación y Desarrollo en Ciencia y Tecnología de los Alimentos (CIDCA), (UNLP - CIC-PBA - CONICET), La Plata 1900, Argentina; Facultad de Ciencias Exactas, Universidad Nacional de La Plata, La Plata 1900, Argentina.

International journal of biological macromolecules

|June 5, 2025

概括

银纳米粒子 (AgNPs) 增强了用于包装的玉米粉薄膜. 激光合成的AgNP提高了特性,但比化学合成更多地降低了细胞活力,强调了AgNP方法的重要性.

科学领域:

材料科学材料科学材料科学
纳米技术纳米技术
生物技术是生物技术.

背景情况:

基于粉的薄膜对可持续包装有希望.
纳米颗粒的结合可以增强薄膜的特性.
控制纳米粒子合成对于性能和安全至关重要.

研究的目的:

开发和比较玉米粉纳米复合膜与银纳米粒子 (AgNPs) 通过激光切除与化学方法合成.
评估这些纳米复合材料薄膜的结构,机械,光学和屏障性能.
评估开发的膜的体外细胞毒性.

主要方法:

使用超短脉冲Ti:Za激光 (AgNP F) 和化学方法合成AgNP.
将AgNP纳入玉米粉膜形成悬浮剂.
使用紫外线光谱,TEM,SEM和机械测试进行表征.
使用Caco-2/TC7和Vero细胞系进行细胞毒性测定.

主要成果:

激光合成的AgNP分散得很好 (半径为3纳米),并无缺陷地集成到粉膜中.
与对照膜相比,AgNP F膜表现出增强的机械,光学和屏障性能.
AgNP F膜降低了Caco-2/TC7细胞活力至66%,而AgNP in situ膜保持了90%的活力.
这两种AgNP类型都影响了Vero细胞的活力.

结论:

在包装应用中,AgNP显著提高了基于粉的薄膜的性能.
合成AgNPs的方法对产生的纳米复合材料薄膜的生物相容性产生了重大影响.
激光辅助合成提供了增强的薄膜特性,但需要进一步调查细胞毒性,以确保安全应用.

关键词:

细胞毒性评价细胞毒性评估物理化学特性物理化学特性粉纳米复合材料的片.

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