在中国进行的一项全国多中心研究中,初次住院治疗初级闭角眼的高失明负担
Kun Xiong1, Huiyan Mao1, Jinyuan Chen2
1National Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.
BMJ open ophthalmology
|June 5, 2025
概括
在中国,超过40%的初级闭角眼患者在住院后失明. 年龄较大,眼内压高,农村居住和较低水平的医院增加了失明的风险.
科学领域:
- 眼科医生 眼科 眼科
- 公共卫生 公共卫生
- 玻璃眼研究研究 玻璃眼研究
背景情况:
- 主要视角闭合型玻璃眼 (PACG) 是全球视力损失的重要原因之一.
- 了解PACG中失明的患病率和风险因素对于有针对性的干预至关重要.
研究的目的:
- 确定中国PACG初次住院时失明的发生率.
- 为了确定与PACG患者失明相关的风险因素.
主要方法:
- 在中国的26家医院中采用了多阶段分层采样方法.
- 在2011年1月至2020年12月期间,从3957名PACG患者收集了数据.
- 后勤回归模型确定了双眼和双眼失明的风险因素.
主要成果:
- 42.7%的PACG患者至少有一只眼睛失明,5.33%的双眼失明.
- 失明的危险因素包括年龄 (60岁以上),眼内压高 (IOP),农村居住和在城市级医院呈现.
- 对于双边失明,也发现了类似的风险因素.
结论:
- 在中国的PACG患者中,很大一部分患有失明.
- 干预措施应优先考虑改善农村,城市级设施的诊断和治疗服务.
- 专注于高IOP的老年患者对于降低PACG相关失明的负担至关重要.
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