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Updated: Jan 18, 2026

A Reporter Assay to Analyze Intronic microRNA Maturation in Mammalian Cells
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Published on: June 16, 2022

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hAgo2的形态动力学沉默:解码跨人类阿尔戈诺特对应器的功能分歧

Antonella Paladino1, Andrea Catte2, Jorge Franco1

  • 1Institute of Biostructures and Bioimaging, IBB-CNR, Via Pietro Castellino 111, 80131 Napoli, Italy.

Journal of chemical information and modeling
|June 5, 2025
PubMed
概括

阿尔戈纳特 (Ago) 蛋白通过RNA干扰控制基因表达. 这项研究揭示了人类Ago异型 (hAgo1-4) 的结构灵活性差异如何决定它们独特的基因沉默功能,活跃的Hago2比刚性Hago4更具动态性.

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