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Updated: Jan 18, 2026

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与增加乳酸细菌存在于捐赠的人类牛奶中相关的因素
Jurjana Novoselac1, Katarina Butorac2, Andreja Leboš Pavunc2
1Clinical Department of Transfusion Medicine and Transplantation Biology, University Hospital Centre Zagreb, Zagreb, Croatia.
概括
纯母乳养母亲捐赠的母乳 (DHM),具有较低的细菌数量和更短的储存时间,更有可能含有有益的乳酸细菌 (LAB). 捐赠者的BMI和哺乳年龄也会影响细菌的存在.
科学领域:
- 微生物学 微生物学
- 新生儿健康 新生儿健康
- 人类牛奶研究研究
背景情况:
- 人体牛奶中的益生菌细菌提供了对早产风险的保护,如死性肠球炎.
- 了解在捐赠人乳 (DHM) 中影响乳酸细菌 (LAB) 的因素,对于优化其使用至关重要.
研究的目的:
- 确定影响捐赠人乳中乳酸细菌 (LAB) 存在的因素.
主要方法:
- 在原始DHM样本上利用下一代测序和选择性微生物培养.
- 与微生物学发现相关联的捐赠者,婴儿和牛奶数据.
- 采用回归建模来预测乳杆菌和Bifidobacterium属的存在.
主要成果:
- 双杆菌的丰度与供体BMI和在特定选择性介质上的生长正相关.
- 乳杆菌的丰度与哺乳期的年龄正相关,与总细菌数量负相关.
- 养方式和牛奶库储存时间是DHM中LAB存在的重要预测因素.
结论:
- 成熟的DHM具有较低的细菌数量,共享后的储存时间较短,并且来自仅母乳养的母亲,据推测含有LAB.
- 这些发现可以为选择和处理DHM的策略提供信息,以最大限度地提高益生菌含量.
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