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Updated: Sep 19, 2025

Methods for Evaluating the Role of c-Fos and Dusp1 in Oncogene Dependence
10:09

Methods for Evaluating the Role of c-Fos and Dusp1 in Oncogene Dependence

Published on: January 7, 2019

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达沙替尼通过降解MCL1来克服抗BCL2抑制的AML细胞,通过降解MCL1来克服AML细胞

Sylvain Garciaz1, Camille Montersino1, Maxence Bourgoin2

  • 1Aix-Marseille Univ, Inserm, CNRS, Institut Paoli-Calmettes, CRCM, Marseille, France.

British journal of haematology
|June 6, 2025
PubMed
概括

达沙替尼 (DASA) 通过降解MCL1.1,有效地向维内托克拉克斯抗性 (VEN-R) 急性髓性白血病 (AML). 这一发现支持对VEN-RAML患者进行新的临床试验.

关键词:
严重的急性白血病.灭症 (apoptosis) 是一种死亡的过程.药物耐药性 耐药性 药物耐药性

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