视觉心理图像和幻觉损伤映射到一个融合的大脑网络上
medRxiv : the preprint server for health sciences
|June 6, 2025
概括
脑部病变引起的幻觉,无法形成视觉心理图像,都与左状回环中的特定区域相连. 这一发现强调了状图像节点对于视觉想象至关重要.
科学领域:
- 神经科学是一个神经科学.
- 认知心理学 认知心理学
- 神经成像是一种神经成像.
背景情况:
- 视觉心理图像使人们能够回忆过去的事件,并想象未来的场景.
- 幻觉,视觉心理图像的缺失,影响大约1%的人口,原因不明.
- 研究由于脑损伤而导致的获得性幻觉症可以揭示视觉图像的关键大脑区域.
研究的目的:
- 确定与损伤诱导的幻觉症相关的特定大脑区域和网络.
- 为了研究脑损伤的功能连接,导致阿芬塔西亚.
- 为了确定是否阿芬坦西亚病变连接到拟议的状图像节点.
主要方法:
- 对病例报告的系统审查,以确定12例病变诱导的食神病.
- 用1000名健康受试者的休息状态fMRI数据分析病变位置及其功能连接.
- 对比 aphantasia 病变网络与在视觉心理图像任务期间的大脑激活.
主要成果:
- 在不同的大脑区域发现了导致花症的病变.
- 所有确定的阿芬塔西亚病变都与左状回形,状图像节点的特定区域功能性地联系在一起.
- 幻病的病变网络与在视觉心理图像中活跃的大脑区域有显著的重叠.
结论:
- 位于左侧状环中的状图像节点是视觉心理图像的关键枢纽.
- 与状图像节点连接的区域的病变可以导致获得的阿芬塔西亚.
- 这项研究提供了对脑损伤位置的临床见解,这可能导致视觉心理图像的丧失.
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