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Updated: Jun 16, 2025

Screening Assays to Characterize Novel Endothelial Regulators Involved in the Inflammatory Response
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炎症诱导的内皮细胞激活和血管新生发芽由基特异性化酶20下调

Bipradas Roy, Jiao-Hui Wu, Neil J Freedman

    bioRxiv : the preprint server for biology
    |June 6, 2025
    PubMed
    概括

    乌比基特异性酶20 (USP20) 抑制了内皮细胞中NFκB信号传递和血管生成. 抑制USP20活动促进血管新生,而其表达减少它,为动脉样硬化和癌症提供治疗潜力.

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