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Updated: Sep 19, 2025

A Restriction Enzyme Based Cloning Method to Assess the In vitro Replication Capacity of HIV-1 Subtype C Gag-MJ4 Chimeric Viruses
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在HIV-1组装过程中逃避CARD8激活

Ivy K Hughes1, James B Hood1, Andrés A Quiñones-Molina1

  • 1Department of Virology, Immunology, & Microbiology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA 02118.

bioRxiv : the preprint server for biology
|June 6, 2025
PubMed
概括

艾滋病毒-1组件由Gag多蛋白协调,以防止过早的蛋白酶活性,逃避CARD8炎症酶. 宿主适应性突变有助于HIV-1逃避细胞死亡,影响人类的病毒进化.

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