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Updated: Jan 18, 2026

Continuous Fluorescence-Based Endonuclease-Coupled DNA Methylation Assay to Screen for DNA Methyltransferase Inhibitors
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Published on: August 5, 2022

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转录因子克服了Polycomb相关甲基化在瘤中的压制性影响

Min-Kyeong Kwon, Goeun Park, Dayoung Go

    bioRxiv : the preprint server for biology
    |June 6, 2025
    PubMed
    概括

    大肠直肠癌 (CRC) 中的DNA甲基化变化并不总是使基因沉默. 尽管DNA高甲基化,但多标记基因可以保持活跃,这表明表观遗传可塑性驱动癌症的进展.

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