治疗时间的可变性 血流感染和与长时间相关的因素的治疗时间的变化
Jesse D Sutton1, Jae Hyoung Lee2, Karen Howard3
1Department of Pharmacy, Veterans Affairs Salt Lake City Health Care System, Salt Lake City, Utah, USA.
Open forum infectious diseases
|June 6, 2025
概括
美国各医院的格拉姆阴性血流感染治疗持续时间差异很大. 治疗时间的中位数为12天,大多数患者接受了超过10天的治疗.
科学领域:
- 传染性疾病 传染性疾病
- 临床药房 临床药房
- 医疗保健管理的管理
背景情况:
- 有限的数据存在于实际的临床环境中,对血流感染的实际治疗持续时间.
- 了解当前的治疗实践对于优化抗菌药物管理和患者结果至关重要.
研究的目的:
- 分析和描述美国多家医院对格兰阴性血流感染的现实治疗持续时间.
- 为了确定这些常见感染的治疗时间的模式和变化.
主要方法:
- 对4240个克负血流感染病例的回顾性分析.
- 在2019年从24个不同的美国医院收集的数据.
- 用于确定中位治疗持续时间和四分位数间范围的描述性统计数据.
主要成果:
- 抗生素治疗的平均持续时间为12天 (四分位数范围:9-15天).
- 大多数患者 (59%) 接受了超过10天的治疗.
- 在参与的医院中观察到治疗持续时间的显著变化.
结论:
- 目前的临床实践中,针对格拉姆阴性血流感染的治疗需要长时间的治疗.
- 实质性的医院间治疗时间变化突出了指导方针开发和标准化的潜在领域.
- 需要进一步的研究,以将治疗持续时间与临床结果和耐药性模式相关联.
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