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系统性红斑狼病修饰在新兴市场的定义和应用:德尔菲小组的共识建议
Guillermo J Pons-Estel1, Odirlei Andre Monticielo2, Edgard Torres Dos Reis Neto3
1Departamento de Medicina Interna, Grupo Oroño-Centro Regional de Enfermedades Autoinmunes y Reumáticas (GOCREAR), Rosario, Argentina.
Lupus
|June 6, 2025
概括
海湾和拉丁美洲的专家支持针对全身性红斑狼 (SLE) 和性炎 (LN) 的疾病修饰框架. 他们强调早期诊断,专家转诊和多学科护理,以获得更好的患者结果.
科学领域:
- 类风湿病学 类风湿病学
- 免疫学 免疫学 免疫学
- 临床实践指南 临床实践指南
背景情况:
- 系统性红斑狼 (SLE) 和狼性炎 (LN) 的疾病修改框架于2022年推出.
- 了解专家对这一框架的接受和应用对于临床实践至关重要.
- 医疗保健系统的区域差异可能会影响这种框架的采用.
研究的目的:
- 评估2022年SLE/LN疾病修改框架的接受和潜在应用.
- 评估来自海湾地区和拉丁美洲的专家意见.
- 确定框架的理解和应用中的任何区域差异.
主要方法:
- 对SLE专家医生进行了两次横截面Delphi调查.
- 在调查之间举行了一场研讨会讨论,以促进共识形成.
- 来自阿根廷,巴林,巴西,墨西哥,阿曼,沙特阿拉伯和阿联的专家参加了会议.
主要成果:
- 在疾病修饰的概念和组件上达成了强烈的共识,但区域差异较小.
- 专家们一致认为,早期诊断,专家转诊以及多学科治疗疾病修饰的重要性.
- 虽然生物标志物被认为是评估疾病修饰的关键,但目前的生物标志物被认为是次优的;免疫抑制剂,生物药物和氧化被认为是疾病修饰的治疗方法.
结论:
- 疾病修饰框架被海湾和拉丁美洲的专家视为管理SLE和LN患者的宝贵工具.
- 专家强调需要明确的临床指导来将框架纳入常规实践.
- 为了成功实施,必须将框架适应不同的当地医疗保健系统.
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