剖析精神分裂症中代理感:一个预测性编码视角
Ileana Rossetti1, Margherita Adelaide Musco1, Lucia Maria Sacheli1
1Department of Psychology and NeuroMi-Milan Centre for Neuroscience, University of Milano-Bicocca, Piazza dell'Ateneo Nuovo, 1 - 20126, Milan, Italy.
Schizophrenia bulletin
|June 6, 2025
概括
精神分裂症患者表现出干扰的行动意识,与健康对照群不同. 这种障碍与幻觉和妄想有关,而不是药物治疗或认知缺陷.
科学领域:
- 认知神经科学 认知神经科学
- 精神病学是一个精神病学.
- 临床心理学 临床心理学
背景情况:
- 在精神分裂症中,主动感的基础上的神经认知过程经常受到干扰.
- 以前的研究没有完全控制时间感知,药物或执行功能等混因素.
研究的目的:
- 为了研究精神分裂症患者的代理感,同时控制潜在的混变量.
- 检查代理干扰,特定症状 (妄想,幻觉,被动性) 和时间感知偏差之间的关系.
主要方法:
- 在30名精神分裂症患者和30名健康对照中利用了故意结合现象,这是一个隐含的代理措施.
- 雇员积极 (自主主动的行动) 和被动 (外部控制的行动) 条件来评估机构.
- 进行全面的神经心理评估和症状评估,包括积极,消极和被动症状.
主要成果:
- 健康对照表现出故意的约束效应,特别是较短的行动-结果延迟.
- 精神分裂症患者表明,故意结合效应的缺失.
- 观察到的代理变化被时间感知偏差,幻觉和妄想显著缓和.
结论:
- 这项研究提供了新的证据,将代理意义上的干扰与精神分裂症的症状学和时间感知联系起来,独立于药物效应.
- 这些发现支持了代理感的预测编码模型,并突出了特定症状在代理缺陷中的作用.
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