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Bone Disorders01:29

Bone Disorders

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Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
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Updated: Sep 19, 2025

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
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Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts

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修改了识别骨质增加的标准.

Jiangjie Chen1,2, Lingling Cao3, Chenghao Xu1

  • 1Bone Metabolism and Development Research Center, Taizhou Hospital Affiliated to Wenzhou Medical University, 150 Ximen St., Linhai, 317000, Zhejiang, China.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
|June 6, 2025
PubMed
概括
此摘要是机器生成的。

扩散性异常性骨超稳定症 (DISH),严重的腰部退行性疾病 (LDD),高体重指数 (BMI) 和糖尿病是超高骨质量 (SEBM) 的关键危险因素. 使用修改的标准将骨质疏松症和骨质疏松症排除在EBM之外.

关键词:
骨矿物质密度 骨矿物质密度伴随性疾病 伴随性疾病诊断标准 诊断标准 诊断标准骨质质量增加 骨质量增加

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Last Updated: Sep 19, 2025

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科学领域:

  • 内分泌学 在内分泌学.
  • 整形外科 整形外科 整形外科
  • 放射学 放射学是一门学科.

背景情况:

  • 矛盾的是,骨质量升高 (EBM) 标准可以包括骨质疏松症/骨质疏松症.
  • 为了准确地定义和研究EBM及其子类型,需要修改标准.

研究的目的:

  • 应用修改后的标准,将骨质疏松症/骨质疏松症排除在EBM之外.
  • 研究EBM的临床影响和风险因素,特别是超级EBM (SEBM).

主要方法:

  • 对33479名参与者 (≥18岁) 的骨矿物质密度 (BMD) 数据 (2021-2023) 的回顾性分析.
  • 根据Z分数定义的正常骨质量 (NBM),EBM,中度EBM (MEBM) 和SEBM.
  • 收集和分析人口统计数据,病史和并发性疾病.

主要成果:

  • 4.4%的参与者患有EBM (3.8%的MEBM,0.6%的SEBM).
  • SEBM组的男性患病率更高,BMI更高,扩散性异常性骨架强症 (DISH),结性脊髓炎 (AS),严重腰部退行性疾病 (LDD) 和糖尿病的患病率增加.
  • 查德分析发现DISH是SEBM最强的预测因素,其次是LDD,BMI和糖尿病.

结论:

  • 修改后的EBM标准,不包括骨质疏松症/骨质疏松症,显示SEBM的并发病率高于MEBM.
  • DISH,严重的LDD,高BMI和糖尿病是SEBM的重要危险因素.