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Assessment of Spontaneous Alternation, Novel Object Recognition and Limb Clasping in Transgenic Mouse Models of Amyloid-β and Tau Neuropathology
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在早期阿尔茨海默氏症药物发现中评估计算和实验方法:系统性审查

Mahir Azmal1, Jibon Kumar Paul1, Md Naimul Haque Shohan1

  • 1Department of Biochemistry and Molecular Biology, Shahjalal University of Science and Technology, Sylhet, 3114, Bangladesh.

Journal of computer-aided molecular design
|June 6, 2025
PubMed
概括

像分子对接这样的计算方法通过快速选化合物来加速阿尔茨海默病 (AD) 药物发现. 将这些in silico方法与实验验证相结合,可以更好地确定有效的治疗方法.

关键词:
乙烯基胆化酶抑制剂的使用阿尔茨海默氏症是阿尔茨海默氏症的一种疾病.分子动力学模拟的模拟.系统性审查系统性审查虚拟选是一个虚拟的选.

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