硬肠炎:对当前文献进行了有针对性的审查
Lefika Bathobakae1, Rammy Bashir2, Atang Koodirile3
1Internal Medicine, St. Joseph's University Medical Center, Paterson, New Jersey, USA.
Scandinavian journal of gastroenterology
|June 6, 2025
概括
艰难肠炎 (CDE) 是一种罕见的小肠感染. 及时的抗生素治疗对于管理CDE和预防严重并发症至关重要,有些病例需要先进的干预.
科学领域:
- 胃肠病学 胃肠病学
- 传染性疾病 传染性疾病
- 微生物学 微生物学
背景情况:
- 硬肠炎 (CDE) 是一种不常见但严重的小肠感染.
- 由于其稀有性,复杂性和非特异性症状,CDE存在诊断挑战.
- 有限的文献和意识有助于延迟诊断和增加患者的发病率.
研究的目的:
- 巩固目前关于CDE流行病学,病理生理学,临床表现和管理的知识.
- 解决关于CDE的现有文献中的关键差距.
- 为改善临床识别和治疗提供全面的概述.
主要方法:
- 针对性地对已发表的案例进行叙事审查.
- 搜索了PubMed,Embase和Web of Science数据库,从创立到2024年4月.
- 包括44篇文章,详细介绍了49例CDE患者病例.
主要成果:
- 该审查分析了49例病例 (51%的男性,49%的女性),年龄从16岁到91岁 (平均53.4岁).
- 常见的症状包括腹痛 (76%) 和腹 (71%).
- 抗生素有效治疗了86%的病例;其他人需要便微生物群移植或手术.
结论:
- CDE是一种严重的疾病,需要及时诊断和治疗.
- 早期干预至关重要,以防止严重的并发症,如肠道穿孔.
- 需要进一步的研究和宣传,以改善CDE的结果.
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