泌尿腺癌:从上到下进行手术期间的考虑
Wesley Yip1, Salvador Jaime-Casas1, Anjaney Kothari1
1Division of Urology and Urologic Oncology, Department of Surgery, City of Hope Comprehensive Cancer Center, Duarte, California, USA.
CA: a cancer journal for clinicians
|June 6, 2025
概括
新型疗法,如免疫疗法和抗体药物合物,正在改善肌肉侵入性膀泌尿腺癌 (UCB) 的治疗结果. 术后护理也在推进膀节省选择和增强的恢复协议.
科学领域:
- 在瘤学瘤学.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
背景情况:
- 尿癌具有显著的发病率,需要在理解和治疗方面取得进展.
- 最近的进展提供了新的治疗和诊断策略,强调以患者为中心的护理.
研究的目的:
- 审查尿癌的新型外科手术周治疗和诊断方法.
- 突出以患者为中心和个性化的护理策略.
- 讨论膀癌和上道泌尿道癌管理方面的进展.
主要方法:
- 对外科手术期间泌尿腺癌治疗的当前文献的综述.
- 专注于新辅助和辅助疗法,包括免疫疗法和抗体药物联合体.
- 评估膀节约方案,器官节约手术和手术后增强康复.
主要成果:
- 非基疗法,免疫疗法和抗体药物合剂扩大了膀肌肉侵入性尿路细胞癌 (UCB) 的治疗选择.
- 正在探索节省膀的协议和改进的外科选择/恢复,以减少发病率.
- 分子分析揭示了上道泌尿道癌和UCB之间的基因组差异,影响了治疗.
结论:
- 术后护理的进步,包括新的疗法和外科手术策略,正在改善尿癌患者的治疗结果.
- 个性化和以患者为中心的方法对于优化治疗至关重要.
- 需要进一步研究上道泌尿瘤和新辅助剂/辅助剂策略.
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