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相关概念视频

Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

3
Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
3
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

8
The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
8

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相关实验视频

Updated: Jun 12, 2025

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
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Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

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系统性硬化和多关节性关节炎之间的重叠:一个案例报告

Geilan A Mahmoud1, Nora Y Elsaid1, Hania S Zayed1

  • 1Rheumatology and Rehabilitation Department, Faculty of Medicine, Cairo University, Egypt.

The Egyptian rheumatologist
|June 6, 2025
PubMed
概括

系统性硬化症 (SSc) 很少与多关节炎 (PAN) 一起发生. 这个案例突出了一个患有SSc的患者,他发展了PAN,需要修改免疫抑制治疗方案才能成功管理.

科学领域:

  • 类风湿病学 类风湿病学
  • 免疫学 免疫学 免疫学
  • 胃肠病学 胃肠病学

背景情况:

  • 系统性硬化症 (SSc) 是一种由血管病变,炎症,自身免疫和纤维化的结合组织疾病.
  • 弗兰克血管炎是SSc患者的一种不常见的表现.

研究的目的:

  • 报告一种罕见的同时存在的系统性硬化症和多关节炎的罕见病例.
  • 讨论这种罕见的关联所需的诊断挑战和治疗修改.

主要方法:

  • 一个36岁男性的病例介绍,患有有限的皮肤SSc.
  • 诊断工作包括血清学测试,成像 (超声波,多普勒扫描,纤维扫描) 和血管炎和肝脏参与的评估.
  • 治疗涉及高剂量的皮质类固醇,血酶,环胺和阿扎西奥普林.

主要成果:

  • 患者出现了瘤,神经病变和丸疼痛,表明血管炎.
  • 肝脏评估显示纤维化和,肝酶水平升高.
  • 诊断为多关节炎结节,患者对强化免疫抑制疗法反应良好.

结论:

  • 系统性硬化和多关节炎的关联非常罕见.
关键词:
乙型肝炎病毒的感染.多膜炎结节症 (polyarteritis nodosa) 是一种多膜炎.系统性硬化症 系统性硬化症血管炎是一种血管炎.

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  • 同存需要量身定制的治疗策略,通常涉及强大的免疫抑制,以管理SSc患者血管炎的严重表现.