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铁素减少酶 (FdxR) 突变的分子基础,导致线粒体形病变

Amit Kumar1, Janie E McGlohon1, D Fernando Estrada1

  • 1Department of Biochemistry, Jacobs School of Medicine and Biomedical Science, University at Buffalo, Buffalo, New York, USA.

Journal of inorganic biochemistry
|June 6, 2025
PubMed
概括

铁素减少酶 (FdxR) 的突变影响其与Fdx1和Fdx2的相互作用,导致神经病变和上腺问题. 蛋白质的不稳定性和降解是FdxR相关疾病的关键原因.

关键词:
电子转移是指电子的转移.铁素减少酶的作用铁素1 是一种铁素.铁素2 铁素2 在弗拉文腺因二核酸 (FAD) 是一种线粒体病变 - - 线粒体病变核磁共振 (NMR) 是一种核磁共振技术.蛋白质的稳定性 蛋白质的稳定性蛋白质与蛋白质的相互作用

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