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Updated: Sep 19, 2025

Detecting the Ligand-binding Domain Dimerization Activity of Estrogen Receptor Alpha Using the Mammalian Two-Hybrid Assay
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Detecting the Ligand-binding Domain Dimerization Activity of Estrogen Receptor Alpha Using the Mammalian Two-Hybrid Assay

Published on: December 19, 2018

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人类雌激素受体连接体结合域对androstenediol识别的结构比较

Jordan L Pederick1, John B Bruning1

  • 1Institute for Photonics and Advanced Sensing (IPAS), School of Biological Sciences, The University of Adelaide, Adelaide, South Australia, 5005, Australia.

Molecular and cellular endocrinology
|June 6, 2025
PubMed
概括

安德二醇与雌激素 (E2) 类似地与雌激素受体 (ERα和ERβ) 结合. 结构分析表明,ERβ选择性源于微妙的口袋差异,但没有观察到明显的结构变化,表明其他因素介于其抗炎作用.

关键词:
5 - 安德二醇的使用.阿迪奥尔 (Adiol) 是一种这是一种雌雄性多醇 (hermaphrodiol).核受体是核受体中的一个.这是一种类固醇.转录因子是一种转录因子.在X射线晶体学.

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