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超加工食品的消费与膝关节关节炎有关:来自关节炎倡议的数据

Zehra Akkaya¹, Wynton M Sims², John A Lynch³

¹Department of Radiology & Biomedical Imaging, University of California, San Francisco, CA, USA; Department of Radiology, Ankara University, Ankara, Turkey.

Osteoarthritis and cartilage

|June 6, 2025

概括

超加工食品 (UPF) 含量高的饮食与膝关节骨关节炎 (KOA) 结果的恶化有关,特别是在女性中. 这项研究强调了UPF对女性KOA症状和进展的不成比例的影响.

科学领域:

营养科学营养科学
类风湿病学类风湿病学
流行病学流行病学

背景情况:

超加工食品 (UPF) 在西方饮食中越来越普遍.
UPF对诸如膝关节骨关节炎 (KOA) 等慢性疾病的影响需要进一步研究.
了解与饮食有关的疾病结果的性别特异性对于有针对性的干预至关重要.

研究的目的:

调查UPF消费与KOA相关的临床和成像结果之间的关联.
探索UPF摄入量与KOA之间的关系中的潜在性别差异.
确定导致KOA进展和症状严重程度的饮食模式.

主要方法:

对来自骨关节炎倡议的4403名参与者的横截面研究.
使用基于食物频率问卷的NOVA分类来评估UPF摄入量.
对混因素进行调整的统计模型,使用交互术语来测试WOMAC分数,软骨厚度和步行速度等结果中的性别差异.

主要成果:

对几个KOA结果观察到显著的性别相互作用,包括疼痛,功能,步行速度和软骨厚度.
较高的UPF摄入量与更严重的疼痛,减少的身体功能,更薄的软骨和更慢的步伐有关,主要是女性.
虽然一些硬度结果显示了相关性,但在邦费罗尼校正后,它们并没有保持显著.

结论:

富含UPF的饮食与较差的KOA结果有关.
妇女似乎不成比例地受到UPF消费的影响.
饮食修改,特别是减少UPF摄入量,可能是管理KOA的关键策略,特别是在女性中.

关键词:

软骨软骨是一种软骨.饮食饮食饮食饮食这就是为什么MRI是MRI.骨关节炎是一种骨关节炎.超加工食品超加工食品超加工食品

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