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相关概念视频

Translation01:31

Translation

Lesson: Translation
Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
Translation Produces the Building Blocks of Life
Translation01:31

Translation

Lesson: Translation
Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
Translation Produces the Building Blocks of Life
Termination of Translation01:44

Termination of Translation

The large ribosomal subunit has several important structures essential to translation. These include the peptidyl transferase center (PTC) - which is the site where the peptide bond is formed - and a large, internal, water-filled tube through which the nascent polypeptide moves. This latter structure is called the Peptide Exit Tunnel, and it begins at the PTC and spans the body of the large ribosomal subunit. During translation, as the nascent polypeptide chain is synthesized, it passes through...
Translation01:31

Translation

Lesson: Translation
Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
Translation Produces the Building Blocks of Life
Termination of Translation01:44

Termination of Translation

The large ribosomal subunit has several important structures essential to translation. These include the peptidyl transferase center (PTC) - which is the site where the peptide bond is formed - and a large, internal, water-filled tube through which the nascent polypeptide moves. This latter structure is called the Peptide Exit Tunnel, and it begins at the PTC and spans the body of the large ribosomal subunit. During translation, as the nascent polypeptide chain is synthesized, it passes through...
Translation01:31

Translation

Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
Translation Produces the Building Blocks of Life
Proteins are called the...

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Author Spotlight: Understanding Age-Related Macular Degeneration Pathophysiology with QAF Workflow
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[翻译文章]OrPhar-SEFH 2024-2027年战略计划

Mónica Climente Martí1, María Dolores Edo Solsona2, María Reyes Abad Sazatornil3

  • 1Servicio de Farmacia, Hospital Universitario Dr. Peset, Valencia, Spain.

Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria
|June 6, 2025
PubMed
概括

在OrPhar-SEFH战略计划2024-2027中,概述了推动医院药房在罕见疾病护理中的作用的关键行动. 它优先考虑合作,证据分析和针对孤儿药物和患者结果的专业服务.

关键词:
多标准的决策分析.这种疾病很少发生.团队是跨学科的跨学科的团队是跨学科的.医疗保健药物 医疗保健药物多个标准的决策分析分析.孤儿药物 孤儿药物 是一种孤儿药物.战略计划 战略计划罕见疾病是一种罕见的疾病.战略计划 战略计划

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科学领域:

  • 药理学和制药科学 药理学和制药科学
  • 医疗保健服务研究 医疗服务研究
  • 罕见疾病管理 罕见疾病管理

背景情况:

  • 罕见疾病的景观为医院药房服务带来了独特的挑战.
  • 现有的结构需要转型,以有效地满足罕见病患者的需求和孤儿药物管理的复杂性.
  • 在OrPhar-SEFH小组认识到需要一个战略计划,以指导医院药剂师在这个专业领域.

研究的目的:

  • 制定OrPhar-SEFH战略计划2024-2027,旨在促进医院药房在罕见疾病领域的转型.
  • 确定影响医院药剂师和罕见病患者的关键趋势,挑战和机会.
  • 定义和优先考虑可行的策略,以加强医院药剂师在罕见疾病护理中的作用.

主要方法:

  • 采用了三阶段的方法:情况分析 (文献综述,访谈,SWOT),行动线路的定义 (分为五个战略轴:联盟,证据,研究/创新,优化,联盟),以及基于影响和可行性的优先级.
  • 与医院药剂师和患者倡导团体 (FundAME,Fedhemo) 进行了采访,以收集不同的观点.
  • 分析侧重于四个变革杆:护理过程转型,患者体验,孤儿药物评估/获取和现实世界的证据.

主要成果:

  • 在五个战略轴上共商定了23条行动线.
  • 主要优先行动包括加强医院药剂师在孤儿药物评估中的合作,加强科学证据的批判性分析,促进孤儿药物的多标准决策分析,将药剂师纳入跨学科团队,并建立专门服务网络.
  • 患者采访突出了医院药剂师的角色,患者体验,教育和治疗准入等方面的需求.

结论:

  • "OrPhar-SEFH战略计划2024-2027"为医院药剂师提供了一份路线图,以改善罕见病管理.
  • 该计划强调加强对孤儿药物的评估和获取,优化护理流程,改善患者的治疗结果和生活质量.
  • 预计战略实施将大大提高医院药房对罕见病患者护理的贡献.