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Updated: Jun 12, 2025

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翻译抑制了外源标RNA介导的微RNA衰变

Tianqi Li1,2,3, Lu Li1,2, Nicholas M Hiers1,2

  • 1Department of Biochemistry and Molecular Biology, University of Florida, Gainesville, FL, 32610, USA.

Nature communications
|June 6, 2025
PubMed
概括

当触发器在编码序列 (CDS) 中并且翻译被抑制时,目标导向的miRNA降解 (TDMD) 得到增强. 这项研究探讨了翻译和TDMD之间的关系,解释了为什么CDS触发器效率较低.

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