相关实验视频
Updated: Jun 13, 2025

05:38
Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
Published on: May 16, 2025
36
皮肤性病晚期和全身性红斑狼:一个病例报告
Jairo Cajamarca-Baron1,2, Juan Sebastian Bonilla Crespo3,4, Angie Tatiana Calderón Vásquez3,4
1Fundación Cardioinfantil - Instituto de Cardiología, Bogotá, Colombia.
Journal of medical case reports
|June 6, 2025
概括
与系统性红斑狼同时发生的皮质晚期和系统性红斑狼是罕见的. 这一案例突显了免疫抑制患者的诊断挑战,强调了病作为狼的潜在早期症状.
科学领域:
- 免疫皮肤学 免疫皮肤学
- 自免疫性疾病 自免疫性疾病
- 肝病学 肝病学是一种肝病学.
背景情况:
- 系统性红斑狼 (SLE) 涉及多个器官和自身抗体.
- 皮质性病后期 (PCT) 通过抑制尿素原脱酶,影响肝脏和皮肤.
- SLE和PCT的同时发生是非常罕见的,特别是在接受免疫抑制剂的移植患者中.
研究的目的:
- 在移植接受者中报告PCT和SLE共存的罕见病例.
- 为了对这种不寻常的关联进行文献审查.
- 为管理复杂病例提供临床参考.
主要方法:
- 一个62岁的女性病例介绍,她有移植病史.
- 临床检查显示了光敏感囊泡病变,超色素和超三症.
- 诊断工作包括免疫分析,尿液尿波氨酸分析和组织病理学.
主要成果:
- 证实了皮肤色素炎和全身性红斑狼的诊断.
- 患者出现了特征性的皮肤病变和尿液变化.
- 用低剂量抗疟药治疗导致了足够的临床反应.
结论:
- 结合诊断PCT和SLE给医生带来了重大挑战.
- PCT可以表现为底层SLE的唯一初始标志.
- 这一案例强调了认识到这种罕见的关联对于及时诊断和治疗的重要性.
相关概念视频
Skin Diseases and Disorders
3.7K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
3.7K
Lysosomal Hydrolases
3.8K
Lysosomes are the site for the degradation of macromolecules and biological polymers released during membrane trafficking events such as secretory, endocytic, autophagic, and phagocytic pathways. The membrane-enclosed area of the lysosome, called the lumen, contains hydrolytic enzymes active in an acidic environment. These acid hydrolases are functional at a pH between 4.5 and 5 and are involved in cellular processes such as cell signaling, energy metabolism, restoration of the plasma membrane,...
3.8K
Changes in Skin Color: Clinical Perspectives
1.8K
The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
1.8K

