在儿科炎性肠病中的量化运动性评估:一个多读者研究
Riwa Meshaka1, Heather E Fitzke2, Joy Barber3
1Great Ormond Street Hospital for Children NHS Foundation Trust, London, WC1N 3BH, UK. riwa.meshaka@gosh.nhs.uk.
Pediatric radiology
|June 7, 2025
概括
在儿科炎性肠病中使用磁共振肠学 (MRE) 量化肠机动性显示出不同经验的读者之间很好的共识,支持其作为生物标志物的使用.
科学领域:
- 胃肠病学 胃肠病学
- 医疗成像医学成像
- 儿科炎症性肠病 儿科炎症性肠病
背景情况:
- 通过磁共振肠道学 (MRE) 测量肠机动性,显示出作为炎症性肠病 (IBD) 生物标志物的潜力.
- 经验丰富的读者已经证明了它在研究环境中的实用性.
研究的目的:
- 为了评估非经验丰富的读者对量化肠动性测量的共识.
- 评估MRE衍生动力指标在儿科IBD中的可靠性.
主要方法:
- 从小儿IBD患者 (<18岁) 的MREs的回顾性分析.
- 量化运动软件用于分析两个MREs的电影图像.
- 使用布兰德-阿尔特曼分析和移动性指数变化百分比协议评估的读者间一致性.
主要成果:
- 在移动性变化方向上观察到相当到非常好的一致性.
- 初级读者与经验丰富的读者一致认为,移动性改变方向的时间为73-84%.
- 高年级读者与经验丰富的读者达成67%-85%的一致意见,对运动率指数变化达成可接受的协议限制.
结论:
- 在儿科IBD中量化肠动性测量在不同经验水平的读者之间是可靠的.
- 这支持了基于MRE的运动性评估作为儿科IBD管理中的可复制生物标志物的潜力.
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