相关实验视频

Updated: Sep 19, 2025

Transmission Electron Microscopy as the Visualization Technique for Analysis of Circadian Synaptic Plasticity in the Mouse Barrel Cortex
12:06

Transmission Electron Microscopy as the Visualization Technique for Analysis of Circadian Synaptic Plasticity in the Mouse Barrel Cortex

Published on: August 19, 2025

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DoliClock:一种基于脂质的衰老时钟揭示了神经系统疾病中的加速衰老

Djakim Latumalea1,2,3, Maximilian Unfried1,3, Diogo Barardo1,3

  • 1Healthy Longevity Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.

Aging
|June 7, 2025
PubMed
概括

这项研究介绍了DoliClock,一个基于脂质的生物衰老钟用于大脑. 它揭示了自闭症,精神分裂症和唐氏综合征的加速衰老,突出了多利霍尔作为一个关键的衰老生物标志物.

关键词:
时钟的老化时间自闭症自闭症是什么杜利科尔科尔是什么意思唐氏综合征是什么意思精神分裂症是一种精神分裂症.

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Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
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