老年人的术后妄想:一个回顾性队列研究
J A Vélez-Restrepo1, P A Betancourt-Ángel2, J D Caicedo-Jaramillo1
1Departamento de Anestesiología, Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia.
Revista espanola de anestesiologia y reanimacion
|June 7, 2025
概括
手术后妄 (POD) 影响了60岁以上的手术患者的6.0%,特别是那些患有先前存在的疾病或正在接受紧急手术的人. 这种情况增加了术后并发症和住院死亡的风险.
科学领域:
- 在外科手术期间的医学.
- 老年医学 老年医学
- 麻醉学 麻醉学
背景情况:
- 手术后痴呆症 (POD) 是老年手术患者的重大不良事件,与较高的发病率,死亡率和成本有关.
- 由于缺乏诊断和预防方案,哥伦比亚的POD报告不足.
- 识别POD发病率和风险因素对于改善患者的治疗结果至关重要.
研究的目的:
- 为了确定60岁以上接受手术的患者中POD的发病率.
- 识别与POD发展相关的潜在风险因素.
- 调查POD和其他术后并发症之间的关联.
主要方法:
- 对2535名60岁以上的患者进行了回顾性队列研究,这些患者在2012年至2019年期间接受了手术.
- 使用随机抽样分析电子病历.
- 在手术后7天内评估POD发生率,危险因素和并发症.
主要成果:
- POD的累积发病率为6.0% (95% CI:5.1%-6.9%),其中67%发生在前3个术后天.
- 关键风险因素包括精神疾病,手术前使用阿片类药物,ASA类III/IV,血管手术,紧急/紧急手术和功能依赖.
- POD与增加的住院死亡率显著相关 (OR 2.9; 95% CI 1.66-5.07).
结论:
- POD是老年手术患者的常见并发症,特别是那些接受紧急/紧急或血管手术的人.
- 具有特定风险因素 (精神病史,功能依赖,ASA类>III) 的患者更容易患POD.
- POD与术后发病率和死亡率的增加有关,这突显了针对性预防和管理策略的需要.
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