亚急性硬化大脑炎作为由于疫苗接种覆盖率低而重新出现的疾病:一系列病例
Gabriella Errichiello1,2, Francesco Tengattini3,4, Silvia Gioacchini5
1Pediatric Neurology Unit, Department of Neurosciences, Santobono-Pausilipon Children's Hospital, Naples, Italy. gabriellaerrichiello29@gmail.com.
Italian journal of pediatrics
|June 7, 2025
概括
亚急性硬化大脑炎 (SSPE) 是一种由麻疹病毒 (MeV) 引起的中枢神经系统进展性疾病. 坚持接种疫苗对于预防SSPE至关重要,特别是随着流行后日益增加的担忧.
科学领域:
- 神经学 神经学
- 病毒学 病毒学
- 免疫学 免疫学 免疫学
背景情况:
- 亚急性硬化大脑炎 (SSPE) 是由持续性麻疹病毒 (MeV) 感染引起的致命中枢神经系统疾病.
- SSPE发生率与麻疹疫苗接种率相反相关.
- 麻疹感染时的年龄较小增加了SSPE风险.
研究的目的:
- 描述SSPE,其临床过程,诊断和治疗.
- 为了提高人们对SARS-CoV-2大流行后SSPE患病率增加的认识.
- 强调为预防SSPE而坚持接种疫苗.
主要方法:
- 疾病描述和特征.
- 审查临床过程,诊断工作和治疗选择.
- 呈现SSPE病例的典型和非典型呈现.
主要成果:
- SSPE呈现出认知和运动能力的下降,在3-4年内进展到死亡.
- 病例突出了不同的临床表现和治疗结果.
- 重点是药理和神经外科干预.
结论:
- 坚持接种疫苗是SSPE预防的唯一有效方法.
- 随着SARS-CoV-2大流行,SSPE患病率的增加是一个令人担忧的问题.
- 提高认识对于公共卫生倡议至关重要.
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