Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Management of Insomnia01:19

Management of Insomnia

328
The sleep cycle, an integral part of human health, consists of several stages with distinct characteristics and functions. It begins with a transition from wakefulness to sleep, known as the light sleep phase, followed by the restorative deep sleep phase, essential for physical recovery and growth. The cycle concludes with the Rapid Eye Movement (REM) phase, characterized by high brain activity and vivid dreaming. Insomnia, a prevalent sleep disorder, involves difficulty falling asleep, staying...
328
Hormonal Control of the Ovarian Cycle01:30

Hormonal Control of the Ovarian Cycle

3.5K
The ovarian cycle is meticulously regulated by the hypothalamic-pituitary-gonadal axis. This cycle orchestrates the release of a mature oocyte, essential for reproduction.
Before puberty, the hypothalamus releases GnRH in a low frequency, low amplitude pulsatile manner. This along with the immature hypothalamic-pituitary-gonadal axis activity, results in low estrogen levels and the absence of a fully functional ovarian cycle.  At puberty, GnRH secretion increases in both frequency and...
3.5K
Hormonal Regulation of the Menstrual Cycle01:22

Hormonal Regulation of the Menstrual Cycle

729
The ovarian cycle regulates endometrial changes throughout a single menstrual cycle via the coordinated action of gonadotrophin-releasing hormone (GnRH) and gonadotrophins.
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH...
729
Menopause01:28

Menopause

269
Menopause, a natural biological process marking the end of a woman's fertility, typically occurs between the fifth and sixth decade of life. This phase is characterized by the exhaustion of the ovarian follicle pool, leading to less responsive ovaries despite the high levels of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). The consequential decrease in estrogen production results in symptoms like hot flashes, heavy sweating, headaches, hair loss, muscle pains, vaginal...
269
The Pineal Gland01:02

The Pineal Gland

2.6K
The pineal gland, a diminutive endocrine structure named for its pinecone-shaped appearance, is situated atop the third ventricle within the diencephalon region of the forebrain. This gland, composed of secretory cells known as pinealocytes arranged in compact cords and clusters around dense particles of calcium salts, plays a pivotal role in hormonal regulation.
The primary secretion of the pineal gland is the hormone melatonin, derived from serotonin. The concentration of melatonin in the...
2.6K
Sedatives and Hypnotics Drugs: Miscellaneous Agents01:17

Sedatives and Hypnotics Drugs: Miscellaneous Agents

249
Sedatives and hypnotics encompass a wide range of substances, each with its unique mechanism of action, uses, and potential adverse effects.
Melatonin congeners like ramelteon (Rozerem) and tasimelteon (Hetlioz) selectively bind to melatonin receptors (MT1 and MT2) and thus mimic the actions of melatonin, a hormone that regulates sleep-wake cycles. Tasimelteon is primarily used for non-24-hour sleep-wake disorder, common in blind patients. They are also used to treat conditions like insomnia...
249

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

An opposite pH-responsiveness "gating" strategy: Intelligent sporopollenin exine armor for targeted therapy of colitis.

Asian journal of pharmaceutical sciences·2026
Same author

Dynamic Transcriptomic Profiling of Mouse Endometrium Across the Estrous Cycle Reveals Phase-Specific Regulatory Networks Underlying Cyclic Remodelling.

Journal of cellular and molecular medicine·2026
Same author

Ion-Triggered In Situ Gel Combined with Melatonin Liposomes: Breaking Through the Dual Barriers of Nasal and Brain Delivery to Treat Insomnia.

Pharmaceutics·2026
Same author

[TCM pathogenesis and acupuncture-moxibustion differentiation and treatment of Crohn's disease based on the "liver-spleen-intestine" axis].

Zhongguo zhen jiu = Chinese acupuncture & moxibustion·2026
Same author

Plastrum Testudinis Extract Ameliorates Intervertebral Disc Degeneration by Suppressing NF-κB Mediated Senescence and Inflammation.

Journal of immunology research·2026
Same author

Resource endowment, medical services utilization and health poverty vulnerability: evidence from middle-aged and older households in rural western China.

Frontiers in public health·2026
Same journal

Ophthalmic artery Doppler: reference values in low-risk pregnant women.

Archives of gynecology and obstetrics·2026
Same journal

Diagnostic and treatment delay in women with cancer in pregnancy: a case-based study.

Archives of gynecology and obstetrics·2026
Same journal

One-year outcome after laser treatment of vulvar lichen sclerosus: a prospective observational trial.

Archives of gynecology and obstetrics·2026
Same journal

Evaluation of the concept of students learning practical gynecological and obstetric skills at a large German university hospital, using the example of the Homburg university women's clinic.

Archives of gynecology and obstetrics·2026
Same journal

Is a history of cesarean section a predictive factor for the failure of medical management in spontaneous abortion?

Archives of gynecology and obstetrics·2026
Same journal

Spontaneous miscarriage and later lifestyle in predicting hazard of premature mortality: a cohort study in UK Biobank.

Archives of gynecology and obstetrics·2026
查看所有相关文章

相关实验视频

Updated: Sep 19, 2025

Human Primary Trophoblast Cell Culture Model to Study the Protective Effects of Melatonin Against Hypoxia/reoxygenation-induced Disruption
12:02

Human Primary Trophoblast Cell Culture Model to Study the Protective Effects of Melatonin Against Hypoxia/reoxygenation-induced Disruption

Published on: July 30, 2016

16.0K

黑色素:对调节卵巢功能的潜在目标.

Jiahui He1, Tiantian Ye2, Keyi Xu2

  • 1Zhuji People's Hospital of Zhejiang Province, Shaoxing, Zhuji, China.

Archives of gynecology and obstetrics
|June 8, 2025
PubMed
概括
此摘要是机器生成的。

黑色素 (MT) 通过抗氧化应激和改善卵子质量来保护卵巢功能. 这一综述强调了MT MT.

关键词:
黑色素是什么 黑色素是什么 黑色素是什么卵巢功能 卵巢功能氧化应激是一种氧化应激.

更多相关视频

Author Spotlight: Overcoming Challenges in Drosophila Sleep Measurement Using DAM System
05:59

Author Spotlight: Overcoming Challenges in Drosophila Sleep Measurement Using DAM System

Published on: October 20, 2023

2.6K
Defining the Program of Maternal mRNA Translation during In vitro Maturation using a Single Oocyte Reporter Assay
08:00

Defining the Program of Maternal mRNA Translation during In vitro Maturation using a Single Oocyte Reporter Assay

Published on: June 16, 2021

4.5K

相关实验视频

Last Updated: Sep 19, 2025

Human Primary Trophoblast Cell Culture Model to Study the Protective Effects of Melatonin Against Hypoxia/reoxygenation-induced Disruption
12:02

Human Primary Trophoblast Cell Culture Model to Study the Protective Effects of Melatonin Against Hypoxia/reoxygenation-induced Disruption

Published on: July 30, 2016

16.0K
Author Spotlight: Overcoming Challenges in Drosophila Sleep Measurement Using DAM System
05:59

Author Spotlight: Overcoming Challenges in Drosophila Sleep Measurement Using DAM System

Published on: October 20, 2023

2.6K
Defining the Program of Maternal mRNA Translation during In vitro Maturation using a Single Oocyte Reporter Assay
08:00

Defining the Program of Maternal mRNA Translation during In vitro Maturation using a Single Oocyte Reporter Assay

Published on: June 16, 2021

4.5K

科学领域:

  • 生殖生物学 生殖生物学
  • 内分泌学 在内分泌学.
  • 细胞生理学 细胞生理学

背景情况:

  • 卵巢功能障碍表现为卵细胞质量降低和卵泡数量减少.
  • 环境因素,毒素和生活方式选择会对卵巢功能产生负面影响.
  • 黑色素 (MT) 是一种内源性抗氧化激素,对生殖细胞具有保护作用.

研究的目的:

  • 审查黑激素在调节卵巢功能中的多方面的作用.
  • 阐明黑激素减轻卵巢衰老和功能障碍的机制.
  • 在临床环境中探索黑激素的治疗潜力.

主要方法:

  • 对有关黑激素和卵巢功能的现有研究的文献综述.
  • 对黑激素的合成,分泌和局部卵巢作用的分析.
  • 检查黑色素对各种卵巢损伤因素的保护作用.

主要成果:

  • 黑素显示出显著的抗氧化和自由基清除特性.
  • MT可以促进卵细胞成熟,受精和胚胎发育.
  • 黑色素减轻由各种有害因素引起的卵巢衰退.

结论:

  • 黑素在维持卵巢功能和延缓衰老方面发挥着至关重要的作用.
  • 了解黑激素的机制为临床干预提供了基础.
  • 对黑素在生殖健康中的治疗应用进行进一步的研究是有必要的.