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甘酸A调节CSF1R以重编程与瘤相关的巨细胞,用于肝细胞癌的免疫治疗

Jiahui Lu1, Tinghuang Zhang1, Chenying Jiang1

  • 1School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang 311402, China.

International immunopharmacology
|June 8, 2025
PubMed
概括

甘酸A (GAA) 通过重编程瘤相关巨细胞 (TAMs) 来抑制肝细胞癌 (HCC). 这种天然化合物增强了巨细胞的抗瘤活性和M1极化,为HCC免疫疗法提供了一种新的方法.

关键词:
殖民地刺激因子1受体 (CSF1R)甘酸A (GAA) 是一种甘酸.肝细胞癌 (HCC) 是一种肝细胞癌.免疫疗法是一种免疫疗法.瘤相关的巨细胞 (TAMs)

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