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在腹部手术后的腹部结合剂:系统性审查和元分析

Jun Watanabe¹, Naoya Kasahara², Yoshiyuki Kiyasu³

¹Department of Surgery, Division of Gastroenterological, General and Transplant Surgery, Jichi Medical University, Shimotsuke-City, Tochigi, Japan; Division of Community and Family Medicine, Jichi Medical University, Shimotsuke-City, Tochigi, Japan.

American journal of surgery

|June 8, 2025

概括

腹部结合剂显著减少术后疼痛和手术部位感染,同时改善腹部手术后的运动能力. 这一元分析支持它们的常规使用,以改善康复和患者的治疗结果.

科学领域:

手术恢复和患者的结果.
医疗设备的有效性医疗设备的有效性
基于证据的医学基于证据的医学

背景情况:

腹部粘合剂通常用于手术后缓解疼痛和帮助移动.
目前的临床指南缺乏强有力的证据来推常规使用粘合剂.
关于腹部结合剂的真正有效性和安全性存在不确定性.

研究的目的:

系统地评估腹部结合剂在治疗术后疼痛方面的疗效.
为了评估腹部结合剂对身体活动的影响,特别是6分钟步行测试.
为了确定腹部结合剂对手术部位感染率的影响.

主要方法:

进行了一项随机效应元分析.
综合了27项随机对照试验 (RCT) 的数据,涉及2741名参与者.
在主要数据库 (MEDLINE,Embase,CENTRAL等) 进行了搜索. 到2024年12月,使用GRADE确定性评估.

主要成果:

腹部结合剂在第1天 (中等确定性) 和第7天 (中等确定性) 减少了术后疼痛.
结合剂的使用在第1天 (高确定性) 和第7天 (中等确定性) 改善了6分钟的步行测试距离.
使用结合剂的患者观察到手术部位感染的显著减少 (中等确定性).

结论:

腹部结合剂在改善术后疼痛和身体功能方面表现出有效性.
使用腹部结合剂与手术部位感染的发病率较低有关.
研究结果表明,患者,外科医生和医疗保健提供者应该考虑腹部结合剂用于腹部手术恢复.

关键词:

腹部粘合剂腹部粘合剂腹部外科手术腹部外科手术流动性流动性流动性疼痛疼痛疼痛疼痛手术部位感染的感染.

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