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Updated: Sep 19, 2025

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基于结构的发现和对蛋白质氨酸酸酶1B的非相模仿双酸抑制剂的构造分析

Sanghwa Yoon1, Juyoung Cho1, Jisu Kim2

  • 1Division of Bio & Medical Bigdata Department (Brain Korea 21 Four), Gyeongsang National University, Jinju 52828, Republic of Korea.

International journal of biological macromolecules
|June 8, 2025
PubMed
概括

研究人员确定了一种新型的非胺基因抑制剂,COM68,用于糖尿病和肥胖的目标蛋白氨酸酸酶1B (PTP1B). 由于有利的特性和有效的抑制,COM68显示了药物开发的潜力.

关键词:
有约束力的自由能源.分子建模分子建模肥胖问题 肥胖问题这就是PTP1B.2 型糖尿病 2 型糖尿病这就是UMAP UMAP.

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