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微导管辅助的微侵袭性玻璃眼手术对开角玻璃眼的疗效和并发症:系统性审查和网络元分析

Luyi Han¹, Yingyan Mao¹, Qing Sang¹

¹Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Beijing Ophthalmology & Visual Sciences Key Laboratory, Capital Medical University, Beijing, China.

Survey of ophthalmology

|June 8, 2025

概括

微导管辅助的MIGS程序为开角玻璃眼提供了与MMC Trab相似的IOP降低. 与MMC Trab.相比,一些MIGS技术显示低血压风险降低,但高血风险增加.

科学领域:

眼科医生眼科眼科
手术创新在外科创新.
视光眼管理视光眼管理

背景情况:

微导管辅助的微侵袭性玻璃眼外科手术 (MIGS) 是一种新兴的替代方法,用于治疗开角玻璃眼 (OAG) 的线粒素C (MMC) 增强型玻璃眼切除术 (MMC Trab).
针对MMC Trab的各种微导管辅助MIGS手术的直接比较疗效和安全性数据有限.

研究的目的:

进行网络元分析 (NMA),比较微导管辅助MIGS程序与MMC Trab.的疗效和安全性.
为了对OAG患者的眼内压力 (IOP) 降低和药物使用的微导管辅助MIGS程序进行排名.

主要方法:

在2009年至2024年的文献中搜索了对微导管辅助MIGS (MAT,GATT,ABiC,ABeC,3T) 和MMC Trab.的研究.
在NMA中包括16项研究 (1081只眼睛),评估3个月和1年后的IOP和药物减少.
评估了手术后不良事件,包括血,内血压升高和低血压.

主要成果:

在1年后,微导管辅助管切除术 (MAT) 与MMC Trab.相比,在IOP降低或药物使用方面没有显著差异.
淋巴镜辅助的透光管切除术 (GATT) 和腹外管整形术 (ABeC) 与低血压风险相比,MMC Trab.的风险较低.
与MMC Trab相比,所有微导管辅助的MIGS手术都显示出高血风险,手术后IOP峰值没有显著差异.

结论:

微导管辅助的MIGS程序,特别是MAT,在一年后在OAG中对IOP控制的有效性与MMC Trab相当.
某些微导管辅助的MIGS技术在降低低血压风险方面提供了潜在的优势,尽管低血压风险增加了.
这些发现为选择小导管辅助的MIGS程序提供了宝贵的比较数据.

关键词:

这就是MIGS.微导管微导管的使用方法开放角度的玻璃眼 (Glaucoma) 是一种骨切除术 (TRABECULECTOMY) 是一种切除骨的方法.

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