前庭过早复杂负担作为 Paroxysmal 前庭动和栓塞性中风的风险分层预测因素
Jin Un Kim1, Alice Snell1, Peter Kabunga1
1Department of Cardiology, Darent Valley Hospital, Dartford, United Kingdom.
概括
通过14天的监测检测到的高心房早发综合体 (APC) 负担强烈预测隐性心房动 (pAF) 和栓塞性中风. 在密码性中风患者中,APC负担可以作为风险分层的替代标记.
科学领域:
- 心脏病学 心脏病学
- 神经学 神经学
- 医疗监测 医疗监测
背景情况:
- 调查密码性中风病因是具有挑战性的.
- 隐性动性心房动 (pAF) 是一个可能的贡献者,但通常会被标准监测遗漏.
- 前庭早产综合体 (APC) 是心房肌病的标志物和AF的预测因素.
研究的目的:
- 用14天的门诊心脏监测来评估APC负担和pAF之间的关联.
- 确定APC负担是否可以作为加密性中风患者风险分层的替代标记.
主要方法:
- 从2022年4月到2023年10月进行回顾性数据收集.
- 包括已确认或怀疑中风/TIA的成年人 (≥18岁),接受14天心脏监测 (Zio XT®).
- 排除100%心房 (AF) 负担的患者.
主要成果:
- 包括454名患者;29名被诊断为pAF.
- APC运行>20与pAF的几率增加了270% (OR:3.70).
- 高APC负担与栓塞性中风有很强的相关性,APC运行>20.20的几率增加 (OR:3.65).
结论:
- APC负担与栓塞性中风密切相关,反映了pAF的病因.
- 高APC负担可能是密码性中风风险分层的有用替代标记.
- 在密码性中风患者的诊断和治疗考虑中,APC识别很重要.
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