在家用漂白剂和度对牙敏感性的影响:系统性审查和网络元分析
Renata Maria Oleniki Terra1, Michael Willian Favoreto2, Tom Morris3
1Department of Restorative Dentistry, School of Dentistry, State University of Ponta Grossa, Uvaranas, Ponta Grossa, PR, Brazil.
Journal of dentistry
|June 8, 2025
概括
较高度的家用牙美白剂,如20-22%的碳胺过氧化物 (CP) 和14-16%的过氧化 (HP),增加牙敏感性 (TS) 的风险. 虽然通常是温和的,但较高度需要谨慎的处方和监督.
科学领域:
- 牙科的美学 牙科的美学
- 生物材料科学 生物材料科学
- 临床牙科 临床牙科
背景情况:
- 牙敏感性 (TS) 是家庭漂白的常见副作用.
- 了解漂白剂度和TS之间的关系对于患者管理至关重要.
- 之前的研究结果各不相同,需要进行全面分析.
研究的目的:
- 系统地审查和执行网络元分析 (NMA) 关于与各种家庭漂白剂和度相关的牙敏感性 (TS) 的风险和强度.
- 为了比较不同氧化 (HP) 和胺 (CP) 度的TS风险和强度.
- 为临床医生提供基于证据的指导,关于在家使用漂白剂的安全使用.
主要方法:
- 在多个数据库 (PubMed,Cochrane Central,LILACS/BBO,SCOPUS,Web of Science,EMBASE) 和灰色文献中进行了系统的搜索.
- 包括随机临床试验 (RCT),比较家庭漂白系统.
- 贝叶斯网络元分析 (NMA) 使用视觉模拟量表 (VAS) 和数值评分量表 (NRS) 疼痛量表评估了TS风险和强度. 评估了偏见风险和证据质量.
主要成果:
- 确定了77项研究,其中50项被纳入了元分析. 大多数研究都显示出偏差的高风险.
- 与HP 2-4%相比,CP 20-22%和HP 14-16%的TS风险较高.与HP 2-4%相比,CP 20-22%和HP 14-16%的TS风险较高. CP 20-22%也显示出比CP 10-11%更高的风险.
- 在CP 20-22%和HP 7-8%上报告了更大的TS强度,而在NRS上CP 10-11%相比. 在VAS上没有发现任何显著差异. 证据的质量很低.
结论:
- 在家用漂白剂的度增加会增加牙敏感性的风险和强度.
- 总的来说,TS在所有药物和度中通常是温和的.
- 由于证据质量低下和研究方案的变化性,研究结果应谨慎解释.
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