针对慢性性耳中炎的局部消毒剂
Karen Head1, Lee Yee Chong1, Mahmood F Bhutta2
1Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK.
The Cochrane database of systematic reviews
|June 8, 2025
概括
针对慢性性中耳炎 (CSOM) 的局部消毒剂显示不确定的效果. 酸耳滴可能有助于排泄的解决,当与抗生素结合时,povidone可能比安慰剂更有效.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 传染性疾病 传染性疾病
- 药理学 药理学是指药理学的学科.
背景情况:
- 慢性性中耳炎 (CSOM) 是一种持续的中耳感染,导致耳部泄漏和听力损失.
- 局部消毒剂是一种潜在的治疗方法,但它们对CSOM的疗效尚不清楚.
- 本综述是对CSOM的非手术干预措施的最新评估.
研究的目的:
- 评估局部消毒剂在治疗慢性性中耳炎的有效性.
- 为了比较局部消毒剂与安慰剂,无治疗或其他局部消毒剂.
主要方法:
- 随机对照试验 (RCT) 的系统审查,包括患有CSOM的成人和儿童.
- 搜索了多个数据库,直到2022年6月.
- 主要结局包括耳部放电和与健康有关的生活质量;次要结局包括听力和并发症.
主要成果:
- 关于局部消毒剂与安慰剂/不治疗的证据非常不确定,因为证据的确定性很低.
- 酒精耳滴中的酸显示出与单独干洗相比,对排泄分辨率的潜在益处.
- 局部用povidone与口服抗生素可能会增加排泄分辨率与安慰剂与抗生素相比.
结论:
- 在CSOM中,局部消毒剂的总体证据的确定性非常低,限制了最终的结论.
- 酸和波维在特定情况下显示出一些前景.
- 没有足够的证据来评估有害影响;需要进一步的研究.
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