胃肠道粘膜活检中的双重感染
J N Aparnna1, Subash Chandra Samal2, Pritinanda Mishra1
1Department of Pathology and Lab Medicine, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.
Indian journal of pathology & microbiology
|June 9, 2025
概括
胃肠道双重感染很罕见,特别是在免疫受损的个体中. 细胞巨乳病毒和强杆菌是最常见的共致病原体,强调了高风险患者需要保持警的必要性.
科学领域:
- 胃肠病学 胃肠病学
- 传染性疾病 传染性疾病
- 病理学 病理学 病理学
背景情况:
- 胃肠道感染对全球发病率和死亡率做出了重大贡献.
- 胃肠道双重感染很少发生,主要发生在免疫受损患者中.
- 第三级护理中心管理复杂的病例,包括具有共感染的病例.
研究的目的:
- 以追溯分析在胃肠道粘膜活检中发现的双重感染的发生和特征.
- 调查与这些双重感染相关的临床情景和并发症.
- 评估胃肠道共感染的诊断挑战和临床影响.
主要方法:
- 从2018年1月到2024年3月进行的回顾性医院观察研究.
- 在6352个内镜粘膜活检中对双重感染的组织形态学的综述.
- 对确诊病例中的临床数据和并发症的分析.
主要成果:
- 胃肠道感染的发病率为21.22%,主要在上部的胃肠道.
- 在195例总感染中,双重感染在10例 (0.74%) 确诊.
- 最常见的共致病原体是细胞巨化病毒 (70%) 和强洛伊德 (Strongyloides stercoralis) (40%),两名患者患上了致命的HLH.
结论:
- 胃肠道双重感染很少见,但危急,特别是在免疫功能低下的患者中.
- 在耐火性炎症性肠病 (IBD) 患者中,应考虑细胞巨乳病毒和斯特朗基洛伊德高感染综合征.
- 及时的组织病理学诊断和临床怀疑对于降低免疫功能受损的患者与胃肠道共感染的死亡率至关重要.
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