右手运动障碍是否会影响帕金森病认知测试的表现?
Priyanka Rao1, Christine A Cooper2, Travis H Turner2
1College of Medicine, Medical University of South Carolina, Charleston, South Carolina, USA.
Movement disorders clinical practice
|June 9, 2025
概括
帕金森病患者 (PwP) 主导手臂的运动障碍没有显著影响图形运动认知测试. 这一发现支持在临床和研究环境中使用这些测试,用于接受深度大脑刺激 (DBS) 的PwP.
科学领域:
- 神经科学是一个神经科学.
- 临床神经学 临床神经学
- 认知心理学 认知心理学
背景情况:
- 占主导地位的上肢运动障碍在帕金森病患者 (PwP) 中很常见.
- 这些障碍会影响日常工作,如写作和打字.
- 它们也可能影响涉及图形运动反应的认知测试结果.
研究的目的:
- 调查上肢损伤与PwP认知测试表现之间的关联.
- 具体地检查图形运动与口语响应任务.
- 在接受深度大脑刺激 (DBS) 的PwP临床样本中评估这种关系.
主要方法:
- 在DBS手术之前,对80个右手占优势的PwP进行了回顾性图表审查.
- 使用MDS-UPDRS第3部分评估右上肢 (RUE) 损伤.
- 使用非参数相关性来分析RUE损伤与图形运动 (例如,Trail Making Test) 和口头任务.
主要成果:
- 在RUE运动障碍和图形运动认知测试表现之间没有发现统计学意义上的关联.
- 这表明,占主导地位的上肢运动缺陷对这一群体的这些特定认知评估没有实质性的影响.
结论:
- 主导RUE损害对图形运动任务的最小影响值得注意.
- 这些发现支持普华永道在临床和研究环境中继续使用图形运动认知测试.
- 这对中等发达的普华永道公司 (PwP) 考虑或接受DBS尤其重要.
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