肌酸激酶作为COVID-19儿童疾病严重性预测剂
Alireza Nateghian1, Marzieh Nojomi2, Mahshid Roohravan Benis2
1Department of Pediatric Infectious Disease, Aliasghar Children's Hospital, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
肌酸激酶 (CK) 水平可以预测儿童的严重COVID-19. 识别这些预测因素有助于早期风险分层和为儿科COVID-19患者提供量身定制的护理,改善结果.
科学领域:
- 儿童传染病 儿童传染病
- 临床生物化学 临床生物化学
背景情况:
- 大多数患有COVID-19的儿童有轻度或没有症状.
- 然而,一小部分儿科患者有严重疾病的风险.
- 识别儿童严重COVID-19的预测因素对于预防和管理至关重要.
研究的目的:
- 为了确定儿童COVID-19严重程度的预测因素.
- 调查实验室标记物和潜在条件在疾病严重性中的作用.
主要方法:
- 一项横截面研究包括德黑兰18岁以下的317名确诊COVID-19或肺部症状的儿童.
- 收集的数据包括人口,实验室和临床参数.
- 使用评分协议评估严重程度,并使用SPSS进行统计分析.
主要成果:
- 肌酸激酶 (CK) 被确定为儿童COVID-19严重程度的重要预测因子.
- 一些实验室标记物包括血红蛋白,AST,ALT,CRP,LDH,D-二次体,费里丁和纤维素显示出与严重性的显著关系.
- 大多数潜在疾病,除了喘,与疾病严重程度的增加有显著的关联.
结论:
- 肌酸激酶 (CK) 可以作为儿童群体中严重COVID-19的预测剂.
- 将CK评估纳入临床实践可以促进及时的风险分层和针对COVID-19儿童的个性化护理.
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