了解 oesophageal 癌症患者现代内镜超声波使用的变化 (价值):多方法研究的协议
Kieran G Foley1, Cherish Boxall2, James Franklin3
1Division of Cancer & Genetics, School of Medicine, Cardiff University, Cardiff, CF14 4XN, United Kingdom.
BJR open
|June 9, 2025
概括
该VALUE研究调查了内镜超声波 (EUS) 如何影响英国食道癌患者的治疗决定. 它的目的是澄清EUS.
科学领域:
- 在瘤学瘤学.
- 医疗成像医学成像
- 胃肠病学 胃肠病学
背景情况:
- 英国每年诊断出9000多名患者患有食道癌.
- 处理决策依赖于放射性分期 (CT,PET,EUS),使用可变的EUS.
- 质疑了EUS在PET-CT引入后的附加值.
研究的目的:
- 了解英国对食道癌症分期使用EUS的差异.
- 确定EUS影响治疗决策的频率和原因.
- 评估患者和临床医生的经验和对EUS的意见.
主要方法:
- 这是一项前性,观察性,多中心的研究,招募了180名可能可治愈的食道癌患者.
- 数据收集包括人口统计,TNM分期,前/后EUS治疗决策和并发症.
- 与多达30名患者和30名临床医生进行定性访谈,以探索态度和经验.
主要成果:
- 招聘计划至2025年9月,结果将在2026年6月之后报告.
- 主要终点:EUS改变治疗决策的病例比例.
- 二级终点:影响EUS使用决策的因素和管理变化的原因.
结论:
- 该VALUE研究将提高对EUS在现代食道癌症分期中的实用性的理解.
- 它将确定影响临床医生和患者EUS决策的关键因素.
- 该研究将量化EUS引导治疗修改的频率.
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