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丹麦与酒精有关的肝炎的发病率和死亡率 - 更新,2016-2023年
Khaibar Ghulam Hazrat1, Sidsel Hyldgaard Støy1, Thomas Damgaard Sandahl1
1Department of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark.
JHEP reports : innovation in hepatology
|June 9, 2025
概括
丹麦与酒精有关的肝炎 (AH) 发病率自2009年以来一直在下降,但在2016-2023年期间稳定下来. 尽管如此,死亡率仍然很高,需要改善这种严重肝病的治疗策略.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 与酒精有关的肝炎 (AH) 是一种严重的肝病,死亡率很高.
- 介绍了2016年至2023年丹麦AH发病率和死亡率的数据.
研究的目的:
- 分析丹麦AH的发病率和死亡率趋势.
- 将当前数据与1999-2008年以前的调查结果进行比较.
主要方法:
- 确定了首次诊断AH和升高胆红素的患者 (2016-2023年).
- 计算了标准化发病率和住院死亡率.
- 与1999-2008年期间的调查结果进行比较.
主要成果:
- 包括1,016名患者;中位数年龄为54.7岁 (66%男性).
- 标准化发病率为每百万/年21.7%,男性和女性均稳定.
- 高死亡率:18%,28天,26%,84天,40% 在365天.
- 中位数MELD得分为26;75%的人患有严重的AH (MELD>21).
- 自2009年以来,发病率大幅下降,反映出酒精销售.
结论:
- 丹麦的AH发病率在2009年后明显下降,但在2016-2023年稳定下来.
- 死亡率仍然很高,这表明需要加强治疗方法.
- 这些发现支持公共卫生倡议和临床管理策略.
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