在多普勒超声波上肝波形变化与肝硬化患者疾病严重程度之间的相关性
Sumaiya Latheef1, Shivanand Patil1, Siddaroodha Sajjan1
1Radiodiagnosis, Shri BM Patil Medical College Hospital and Research Centre, Bijapur Lingayat District Educational Association (BLDE) (Deemed to be University), Vijayapura, IND.
Cureus
|June 9, 2025
概括
对肝静脉波形的多普勒超声波分析可靠地表明肝硬化严重程度,与查尔德-皮格分数相关. 这种非侵入性方法在检测晚期肝病时具有很高的灵敏度.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 医疗成像医学成像
- 心血管生理学心血管生理学
背景情况:
- 肝硬化代表末期慢性肝病,其特征是纤维化和肝脏血液动力学变化.
- 多普勒超声波通过肝静脉波形分析非侵入性地评估这些血液动力学变化.
研究的目的:
- 评估肝静脉波形变化与肝硬化严重程度之间的相关性 (查尔德-皮格得分).
- 评估多普勒波形分析用于肝硬化临床分期的诊断性能.
主要方法:
- 140名确诊肝硬化患者的前性观察性研究.
- 肝血管的多普勒超声学用于分类波形模式 (三相,两相,单相).
- 与Child-Pugh分类,人口统计和实验室参数的相关性分析.
主要成果:
- 在波形模式和肝硬化严重程度之间发现了显著的关联 (p < 0.001).
- 单相和双相波形在晚期肝硬化 (Child-Pugh C级) 中普遍存在.
- 波形分析显示100%的灵敏度和69.5%的预测值对晚期肝硬化.
结论:
- 肝静脉多普勒波形分析是肝硬化严重程度的可靠,非侵入性指标.
- 该方法与Child-Pugh分类有很强的相关性,有助于临床分期.
- 高灵敏度和NPV支持其作为晚期肝病查工具的使用.
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