在患有甲状腺功能低下的女性患者中,通过层特异性菌株评估左心室区域心肌功能
Xiao Ding1, Xijun Zhang1, Changhua Wei1
1Department of Ultrasonography, Henan Provincial People's Hospital, Zhengzhou Henan, China.
Frontiers in cardiovascular medicine
|June 9, 2025
概括
女性甲状腺功能低下会影响左心室肌肉功能,特别是影响周围应变比纵向应变更大. 层特异性菌株分析揭示了患者和健康对照之间的显著差异.
科学领域:
- 心脏病学 心脏病学
- 内分泌学 在内分泌学.
- 医疗成像医学成像
背景情况:
- 甲状腺功能低下会影响心血管功能.
- 左心室心肌功能对整体心脏健康至关重要.
- 层特异性菌株分析为区域心肌力学提供了详细的见解.
研究的目的:
- 为了研究使用层特异性菌株的低甲状腺症女性患者和健康对照者之间的左心室18段心肌功能差异.
- 为了确定外围或纵向应变是否更容易受到甲状腺功能低下的影响.
主要方法:
- 在32名女性甲状腺功能低下患者和30名健康女性志愿者身上进行了二维回声心脏图谱.
- 离线分析测量了内心,心肌中部和心表层的峰值缩周围应变 (PCS) 和峰值缩纵向应变 (PLS).
- 在甲状腺功能低下组 (HG) 和对照组 (CG) 之间进行了层特异性应变值的比较.
主要成果:
- 与CG相比,在HG中观察到后壁中间段的内心纵向应变减少.
- 在所有壁面的HG的尖端段中,注意到心肌和心表周围应变的减少.
- 在 HG 患者的左心室中部和基底部分发现了各种周围应变参数的显著减少.
结论:
- 层特异性菌株分析显示,与健康对照人群相比,女性甲状腺功能低下症患者的左心室肌肉功能模式不同.
- 在低甲状腺症中评估区域左心室功能时,周围菌株对甲状腺激素异常比纵向菌株更敏感.
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