预防新生儿死性肠球炎的质量改善干预措施:系统性审查
Xueli Zhang1, Mingqiu Chen1, Yanfei Zhang1
1Division of Neonatology, People's Hospital of Longhua, Shenzhen, Guangdong, China.
质量改善干预措施 (QIIs) 在减少早产婴儿死性肠球炎 (NEC) 方面表现有前途. 虽然许多QIIs,特别是那些促进母乳养的QIIs,显著降低了NEC发病率,但结果在不同环境中各不相同,表明需要进一步研究.
科学领域:
- 新生儿医学 新生儿医学
- 儿科手术 儿科手术
- 公共卫生 公共卫生
背景情况:
- 死性肠球炎 (NEC) 是导致早产新生儿胃肠道疾病死亡的主要原因.
- 质量改善包旨在减少早产婴儿的NEC发病率,但新生儿重症监护室的结果不一致.
研究的目的:
- 评估旨在预防或减少早产婴儿NEC严重性的质量改善干预措施 (QIIs).
- 确定有效的策略来减少NEC的发病率和严重程度.
主要方法:
- 对多个数据库 (PubMed,Embase,Cochrane图书馆,科学网,万芳,CNKI,VIP,CBM) 的系统审查和引用搜索.
- 包括13项质量改善干预措施,涉及17961名早产婴儿.
- 通过配对审查人员提取数据,重点关注NEC发病率和严重程度的降低.
主要成果:
- 大多数QII都包含了改善母乳养的策略.
- 在19项干预中,16项干预在实施后显著减少了NEC发病率.
- 干预措施的质量一般为中高,尽管研究异质性得到了注意.
结论:
- QIIs可以降低早产婴儿的NEC发病率和严重程度,但效果因环境而异.
- 对于QIIs成功差异的具体机制和原因尚不清楚.
- 这一审查有助于团队识别潜在的优越实践,以减少NEC.
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