便秘与囊性纤维化病的医院利用率增加有关:国家住院样本分析
Matt Pelton1, Arvind Bussetty1, Sarah Abdel-Meguid1
1Internal Medicine, Rutgers Robert Wood Johnson, New Brunswick, New Jersey.
Gastro hep advances
|June 9, 2025
概括
囊性纤维化 (CF) 患者的便秘显著增加了住院时间和医疗费用. 这种效应在患有胰腺功能不全的CF患者中更为明显.
科学领域:
- 胃肠病学 胃肠病学
- 肺部病理学 肺部病理学
- 卫生经济学 卫生经济学
背景情况:
- 便秘是囊性纤维化 (CF) 患者的常见和衰弱症状.
- 在CF患者中,严重的便秘可能导致远端肠道阻塞综合征.
- 了解便秘对住院结果的影响对于患者护理至关重要.
研究的目的:
- 描述住院期间便秘及其相关症状,并发症和CF患者的医疗费用之间的关系.
- 为了比较CF和便秘患者的住院结果与没有CF和便秘患者的住院结果.
- 分析便秘对住院CF患者住院时间和总费用的影响.
主要方法:
- 利用国家住院患者样本数据库从2015年至2019年出院.
- 根据并发症指数,住院严重程度和人口统计数据,将CF住院患者与普通人群进行匹配.
- 为了进行比较分析,创建了有或没有并发性便秘的队列,并根据相关的共变量进行调整.
主要成果:
- 患有CF的住院患者中有14.0%患有便秘,而一般人群中有5.6%.
- 便秘独立地与停留时间增加1.22天和CF患者额外费用增加14,280美元有关.
- 较高成本与便秘的关联在患有胰腺功能不全的CF患者中显著增加.
结论:
- 住院患有CF患者的并发性便秘与住院时间和医疗费用增加独立相关.
- 便秘的经济负担在患有胰腺功能衰竭的CF患者中加剧.
- 这些发现强调了住院CF患者控制便秘的重要性,以减轻不良结果和降低成本.
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