肝脏疾病和植物疗法
Syed Sanober Qadri1, Darakhshan Javaid1, Adfar Reyaz1
1Toxicology and Pharmacology Laboratory, Department of Zoology, School of Biosciences and Biotechnology, Baba Ghulam Shah Badshah University, Rajouri, Jammu and Kashmir 185234, India.
药用植物显示出对肝脏健康的承诺,提供天然化合物来对抗ALD和NAFLD等肝脏疾病. 本综述探讨了它们克服传统治疗方法局限性的潜力.
科学领域:
- 肝病学和药理学 肝病学和药理学
- 自然产品化学 自然产品化学
背景情况:
- 肝脏对于新陈代谢和排毒至关重要,但面临着酒精性肝病 (ALD),非酒精性脂肪性肝病 (NAFLD) 和肝癌等疾病的威胁.
- 目前治疗肝脏疾病的方法经常面临挑战,包括耐药性,不良副作用和高成本,特别是在资源有限的环境中.
- 药物诱导性肝损伤 (DILI) 仍然是一个重要的临床问题.
研究的目的:
- 审查肝损伤的机制.
- 突出传统使用的药用植物在预防和治疗肝脏疾病方面的治疗潜力.
- 强调传统医学与现代药理学研究的整合.
主要方法:
- 科学数据库的文献审查.
- 对已报告具有肝保护作用的药用植物研究的分析.
- 检查生物活性化合物及其药理作用.
主要成果:
- 许多药用植物都含有生物活性化合物,如类化合物,糖类化合物和黄类化合物,具有已证明的肝保护性质.
- 这些天然剂可以减轻肝损伤,调节免疫反应,并有助于管理慢性肝病.
- 传统医学为肝脏疾病的传统疗法提供了一种可行的替代或补充方法.
结论:
- 药用植物是新型肝脏保护剂的有希望的来源.
- 将传统知识与现代科学相结合,可以为肝脏疾病提供有效且易于获得的治疗方法.
- 需要进一步的研究来验证和开发用于肝脏健康的植物性疗法.
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