在1990年至2021年期间,对中国和全球肝癌负担趋势的比较分析
Chunrong Chen1, Qianjie Xu2, Tao Wang1
1Department of Health Information Management, School of Public Health and Management, Chongqing Three Gorges Medical and Pharmaceutical College, Chongqing, China.
Frontiers in public health
|June 9, 2025
概括
在中国,肝癌负担有所下降,死亡率和残疾调整寿命年 (DALYs) 比全球平均水平低. 针对性预防至关重要,特别是对于中国男性来说,由于持续存在的危险因素.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 在瘤学瘤学.
背景情况:
- 2021年全球疾病,伤害和风险因素负担研究 (GBD) 提供了有关全球肝癌负担的数据.
- 了解中国和全球肝癌趋势对于公共卫生战略至关重要.
研究的目的:
- 从1990年到2021年,分析和比较中国和全球肝癌负担趋势.
- 确定肝癌发病率,流行率和死亡率的人口和区域差异.
主要方法:
- 利用GBD 2021数据库的数据,涵盖了204个国家和地区.
- 为发病率,流行率,死亡率和DALYs计算的年龄标准化和原始率.
- 雇员Joinpoint回归分析以评估负担趋势的平均年百分比变化 (AAPC).
主要成果:
- 肝癌病例在中国和全球增加,但年龄标准化发病率 (ASIR) 在中国下降,而在全球略有增加.
- 年龄标准化流行率 (ASPR) 在中国保持稳定,但在全球范围内上升.
- 年龄标准化死亡率 (ASMR) 和DALY率 (ASDR) 在中国和全球都下降,男性的死亡率高于女性.
结论:
- 三十年来,中国的肝癌负担显著下降,超过了全球的减少.
- 尽管情况有所改善,但中国的肝癌负担仍然高于全球平均水平,需要有针对性的预防.
- 中国男性肝癌患病率早些时候达到峰值,这凸显了针对病毒性肝炎,酒精,肥胖和吸烟等危险因素的专注干预的必要性.
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