免疫能力较强的儿童患有胸痛的肺部密码球菌病:三个病例报告
Xiao-Nan Li1, Jie-Hua Chen2, Zhi-Wei Lu3
1Department of Respiratory Diseases, Shenzhen Children's Hospital, Shenzhen 518038, Guangdong Province, China.
World journal of clinical cases
|June 9, 2025
概括
肺部密码球菌病 (PC) 可以影响健康的儿童出现胸痛. 早期诊断和治疗对于在这些具有挑战性的病例中获得更好的结果至关重要.
科学领域:
- 医学真菌学 医学真菌学
- 儿童传染病 儿童传染病
- 肺部病理学 肺部病理学
背景情况:
- 加密球菌是一种机会性真菌,会引起各种感染.
- 肺部加密球菌病 (PC) 越来越多地被诊断为免疫能力强的人.
- PC诊断具有挑战性,特别是在非艾滋病毒患者中,可能导致传播和高死亡率.
研究的目的:
- 总结三个具有免疫能力的儿童的临床特征,PC呈现胸痛.
- 提高临床医生对患有胸痛的儿科患者PC的认识.
- 通过早期诊断和治疗来降低PC相关的死亡率.
主要方法:
- 三名免疫能力强的儿科患者的回顾性病例系列.
- 胸痛的临床表现,没有咳或发烧.
- 诊断方法包括胸部CT,肺活检,Cryptococcus培养和血清抗原检测.
主要成果:
- 胸部CT显示有巩固和空洞化的胸腔基结块.
- 通过组织培养和洗液识别了Cryptococcus.
- 所有患者对口服可纳反应良好,在随访CT时病变明显消失.
结论:
- 肺部加密球菌病可能发生在免疫能力较强的儿童中.
- 胸痛作为一种孤立的症状,需要对儿童的PC保持警.
- 及时诊断和适当的治疗对于防止误诊和改善预后至关重要.
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