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Updated: Jun 12, 2025

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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作为分子模板的化阿尼林,可以在有机共晶体内实现 [2 + 2] 循环添加反应

Grace K White1, Daniel K Unruh2, Herman R Krueger1

  • 1Department of Natural Sciences and Mathematics, Webster University, St. Louis, Missouri 63119, United States.

ACS omega
|June 9, 2025
PubMed
概括

化阿尼林和转-1,2-bis-(4-皮里迪尔) 乙烯形成共晶体,在紫外线下经历 [2+2] 循环添加. 这种反应产生立体选择性光产物,由结和pi堆叠相互作用驱动.

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