相关实验视频
Updated: Jun 12, 2025

Design and Optimization Strategies of a High-Performance Vented Box
Published on: June 9, 2023
储存环境和包装材料对Citri Reticulatae Pericarpium中生物活性化合物的影响
Mengdie Peng1, Jinji Deng1, Jiepei Xu1
1Guangzhou Municipal and Guangdong Provincial Key Laboratory of Molecular Target & Clinical Pharmacology, The NMPA and State Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences and the Affiliated Traditional Chinese Medicine Hospital Guangzhou Medical University Guangzhou China.
广 (GCP),一种药用果皮的最佳储存需要避免极端的温度和湿度. 适当的包装,就像聚乙烯袋一样,在老化过程中保留了关键的生物活性化合物.
科学领域:
- 食品科学与技术 食品科学与技术
- 植物化学 植物化学
- 传统中国医药 传统中国医药
背景情况:
- 广陈皮 (GCP),老化的果皮 (≥3年),具有重要的药用和价值.
- 缺乏标准化的储存准则阻碍了工业生产和GCP的质量控制.
- 优化储存对于保存生物活性化合物和确保适当成熟至关重要.
研究的目的:
- 系统地评估温度,湿度和容器材料在储存期间对GCP化学成分的影响.
- 确定最佳的储存条件,以保护生物活性化合物和标准化GCP质量.
- 为工业化储存广晨平提供科学指导方针.
主要方法:
- 在不同条件下 (温度,湿度,容器类型) 进行了超过24个月的储存实验.
- 使用紫外线光谱光度计量总黄,聚甲黄和酸的量化.
- 通过HPLC-PDA对八个关键生物活性标记物的分析 (例如,hesperidin,ferulic acid) 和通过GC-MS对挥发性油的分析.
- 使用DPPH测定对抗氧化剂活性的评估.
主要成果:
- 低温/低湿度 (4°C/35%-40%) 抑制了GCP的衰老.
- 高温/高湿度 (35°C/>85%) 加快了酸的形成 (7倍),但减少了总的黄酸和甲基2-胺基酸盐.
- 聚乙烯 (PE) 袋保存的总黄和hesperidin比gunny袋更好,其中显示出显著的甲基2-甲基胺) 酸盐损失.
结论:
- 储存条件 (温度,湿度,容器) 在老化过程中极大地影响了GCP的化学特征.
- 避免长时间暴露于极低或极高的温度/湿度对于质量标准化至关重要.
- 建议在晚期储存时使用像PE袋这样的透氧容器,以保持生物活性化合物的完整性.
更多相关视频
07:07Controlled-release of Chlorine Dioxide in a Perforated Packaging System to Extend the Storage Life and Improve the Safety of Grape Tomatoes
Published on: April 7, 2017
14:39Semi-Targeted Ultra-High-Performance Chromatography Coupled to Mass Spectrometry Analysis of Phenolic Metabolites in Plasma of Elderly Adults
Published on: April 22, 2022
相关概念视频
Fruit Development, Structure, and Function
Factors Affecting Dissolution: Drug Permeability, Stability and Stereochemistry
Factors Influencing Drug Absorption: Pharmaceutical Parameters
Assembly of the Lipid Bilayer in the ER
A large chunk of any biological membrane is composed of phospholipids. These lipids have a heterogeneous distribution across different subcellular organelles and even between...
Seed Structure and Early Development of the Sporophyte
Factors Influencing Drug Absorption: Physicochemical Parameters
Enhanced drug absorption can be achieved by reducing particle sizes and increasing surface areas, thereby facilitating...